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Jennifer Delda
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deldaj@asme.org



 









KEYNOTE


Keynote presentation to discuss...

"Trends in Biological Manufacturing - How will our industry change in the next 10 years?"
- Nigel Darby, General Manager BioTechnologies, GE Healthcare Life Sciences


The past 10 years has seen a revolution in the development of new biotherapeutics and vaccines, significantly expanding the range of treatment options. Effective manufacturing is the key to delivering these medicines rapidly to the broadest patient population and in the most cost effective manner. The industry is increasingly challenged to develop technologies to manufacture new types of therapeutics, whilst reimbursement pressures demand significant reduction in costs. At the same time increasing regulatory scrutiny is driving constant improvement in process and product quality.


To meet these challenges manufacturing technology is evolving rapidly. The presentation will consider the likely trends in biological's manufacturing over the next 10 years and how it's evolving to meet the demands of the industry. What new treatment options will emerge from the pipeline and how will this affect our manufacturing infrastructure? How will we deal with the increasing pressure on reimbursement to manufacture therapies more cost effectively? How do we increase the flexibility and responsiveness of our manufacturing infrastructure to deal with threats such as pandemic influenza? How can we facilitate an increase in industry productivity to get candidate drugs to the clinic more rapidly? These questions and more will be considered as we examine the future of this rapidly developing industry.




Nigel Darby joined GE Healthcare Life Sciences in 2003 and is currently General Manager for BioTechnologies and Chief Technical Officer for GE Life Sciences. The BioTechnologies business is a leading supplier of products, technologies and services for a wide variety of applications, including biopharmaceutical and vaccine manufacturing, protein purification and analysis, cell technology, biosensors and drug discovery.


From 1997-2003 Darby held a number of positions with AstraZeneca, finally as Vice-President for Chemistry Technology, with responsibility for teams in Sweden, the U.K, Australia and the U.S.A. In this role, he led the development of new approaches to lead discovery and core facilities in compound management, HTS, structural biology, natural product chemistry, computational chemistry and combinatorial chemistry.


Prior to entering the pharmaceutical industry Darby had spent 16 years in academic research in medicine and molecular biology with positions at the National Institute for Medical Research in London, the M.R.C Laboratory of Molecular Biology, Cambridge and at the European Molecular Biology Laboratory in Heidelberg, Germany.


Darby received his M.A in Natural Sciences from the University of Cambridge in 1981 and his Ph.D in drug metabolism from the University of Kent in 1985.

 

 





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