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Description
This seminar is designed to give the participant a basic understanding
of key issues in designing and implementing a purification process for
the production of a biopharmaceutical material. Scale-up of chromatographic
and filtration operations will be discussed in detail with attention validation
issues. Process scenarios for recombinant proteins and antibodies will
be used to further the basic concepts.
What You Will Learn
- Understand
and apply basic scale parameters in chromatography and filtration
- Understand
the basics of validation and how they impact process design
- Process
requirements and analytical techniques used to judge quality in manufacturing
Who
Should Attend
This seminar is intended for professionals involved in the design, scale-up
and operation of bioprocesssystems. Materials presented in this course
will be of benefit to process, project and manufacturing engineers and
scientists entering the field or requiring further background in specific
separation technologies.
Instructor/Speaker
Panel
- Rolf
Hjorth, Staff Research Engineer, GE Healthcare Bio-Sciences
- Dr.
Kjell Eriksson, Senior Scientist, R&D, GE Healthcare Life Sciences
- Phil
Nelson, Principal Engineer, Process Development, AMGEN
- Craig
Robinson, Technical Director, GE Healthcare Life Sciences
SCHEDULE
|
Monday,
23
June 2008
|
| 7:30
am - 5:00 pm |
Registration
Desk Open |
| 7:30
am - 8:00 am |
Coffee
& Pastries |
| 8:00
am - 10:00 am |
Basic
Concepts in Chromatography
A discussion of chromatographic techniques,
nomenclature, & metrics used in process development. |
Rolf
Hjorth
Staff Research Engineer
GE Healthcare Bio-Sciences
|
| 10:00
- 10:30 am |
Refreshment
Break |
| 10:30
am - Noon |
Critical
Aspects of Chromatographic Process Design
A
discussion of how to design a scalable & robust multi-step purification
strategy.
|
Rolf
Hjorth
Staff Research Engineer
GE Healthcare Bio-Sciences
|
| 12
Noon - 1:00 pm |
Lunch |
| 1:00
pm - 3:00 pm |
Process
Design I: Membrane Process
A review of the critical aspects of membrane
system process design & integration with chromatography processes. |
Craig
Robinson
Technical Director, North Am & Europe
GE Healthcare Life Sciences
|
| 3:00
pm - 3:30 pm |
Refreshment
Break |
| 3:30
- 5:30 pm |
Process
Design I: Membrane Process - cont'd.
A review of the critical aspects of membrane
system process design & integration with chromatography processes. |
Craig
Robinson
Technical Director, North Am & Europe
GE Healthcare Life Sciences
|
|
Tuesday,
24
June 2008
|
| 7:30
am - 8:00 am |
Coffee
& Pastries |
| 8:00
am - 10:00 am |
Process
Design II
Optimizing
and maintaining the process.
|
|
| 10:00
- 10:30 am |
Refreshment
Break in Exhibits Hall |
| 10:30
am - Noon |
Process
Design II - cont'd.
Optimizing
and maintaining the process.
|
|
| 12
Noon - 1:00 pm |
Lunch
w/
Exhibitors |
| 1:00
pm - 3:00 pm |
Production
Scenario: Antibody Production Process
Elements of a monoclonal antibody purification
process
|
Phil
Nelson
Principal
Engineer, Process Development
Amgen
|
| 3:00
- 3:30 pm |
Refreshment
Break in Exhibits Hall |
| 3:30
- 5:00 pm |
Production
Scenario: Antibody Production Process - cont'd.
Elements of a monoclonal antibody purification process
|
Phil
Nelson
Principal
Engineer, Process Development
Amgen
|
| 5:15
- 6:00 pm |
Keynote: "Trends
in Biological Manufacturing - How will our industry change in the
next 10 years?"
-
Nigel Darby, General Manager BioTechnologies, GE Healthcare Life Sciences |
| 6:00
- 7:30 pm |
Networking Reception in Exhibits Hall |
|
Wednesday,
25 June 2008
|
| 8:00
am - 9:00 am |
Workshop:
Learn about the BPE (BioProcessing Equipment) International Standard
|
| 9:30
am - |
BPE
Subcommittee Meetings: Open to the Public |
| 3:30
pm - 5:30 pm |
Plant Tours: GE Healthcare Uppsala / Alfa Laval Tumba (Seats are limited.
Advance sign-up required.) |
REGISTER NOW!
Visit www.asmeconferences.org/BioprocessEurope08
ASME
Travel Policy : ASME
is not responsible for the purchase of non-refundable airline tickets
or the cancellation/change fees associated with canceling a flight. Please
call to confirm that the course is running before purchasing airline tickets.
ASME retains the right to cancel a course up until 3 weeks of the scheduled
presentation date.
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